By: Mónica Sousa, i3S de la Universidad de Oporto (Portugal).
When: October, 4 - 11AM
Where: Sala de Seminarios, ICMM
Abstract: It is widely documented that the adult mammalian central nervous system does not regenerate. This failure results from the inhibitory scar environment and the decline of developmental growth programs. Overturning this dogma, we recently demonstrated that the spiny mouse (Acomys cahirinus) regenerates spontaneously the spinal cord, with robust functional recovery. Our current preliminary data support that an early switch occurs in the injured Acomys spinal cord, allowing scar reversion and activation of a regenerative program. In this talk, I will present and discuss our recent findings on the mechanisms supporting spinal cord regeneration in the spiny mouse and how these may be translated in the future.
