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About

The Materials Science Institute of Madrid (ICMM) is a research centre of the Spanish National Research Council (CSIC) that belongs to the area Materia.

 

Our mission is to generate new fundamental and applied knowledge on materials and processes with added value, and their transfer to the productive sectors at the local, national and European scales. We are involved in the training of new professionals on materials research, and in the dissemination of the scientific knowledge.

 

We embrace diversity, and we defend inclusive science as the only possible one.

 

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Exploring spin physics with topological materials
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In the awards ceremony of the XV National Meeting on Electroceramics, Lorena Pardo from ICMM has been awarded the Gold Epsilon as recognition for a fruitful career dedicated to Electroceramics

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Selective Magnetic Nanoheating: Combining Iron Oxide Nanoparticles for Multi-Hot-Spot Induction and Sequential Regulation

Ovejero J.G., Armenia I., Serantes D., Veintemillas-Verdaguer S., Zeballos N., López-Gallego F., Grüttner C., De La Fuente J.M., Puerto Morales M.D., Grazu V.



The contactless heating capacity of magnetic nanoparticles (MNPs) has been exploited in fields such as hyperthermia cancer therapy, catalysis, and enzymatic thermal regulation. Herein, we propose an advanced technology to generate multiple local temperatures in a single-pot reactor by exploiting the unique nanoheating features of iron oxide MNPs exposed to alternating magnetic fields (AMFs). The heating power of the MNPs depends on their magnetic features but also on the intensity and frequency conditions of the AMF. Using a mixture of diluted colloids of MNPs we were able to generate a multi-hot-spot reactor in which each population of MNPs can be selectively activated by adjusting the AMF conditions. The maximum temperature reached at the surface of each MNP was registered using independent fluorescent thermometers that mimic the molecular link between enzymes and MNPs. This technology paves the path for the implementation of a selective regulation of multienzymatic reactions.

Nano Letters

Specific magnetic features of each MNP generate a different heating power when exposed to AMFs. (a) Magnetization-field hysteresis loops of MNPs under a quasistatic condition. (inset) The central part of a cycle. (b) SAR of MNPs exposed to AMF of 16 mT at increasing frequencies. SAR vs HMAX dependence of MNPs exposed to (c) low-frequency AMF (96 kHz) and (d) high-frequency AMF (760 kHz).

ICMM-2021 - Sor Juana Inés de la Cruz, 3, Cantoblanco, 28049 Madrid, Spain. Tel: +34 91 334 9000. info @ icmm.csic.es