ASOCIACION ESPAñOLA DEL VACIO Y SUS APLICACIONES
INSTITUTO DE CIENCIA DE MATERIALES DE MADRID - CSIC

CSIC

ASEVA SUMMER SCHOOL FOR VACUUM AND APPLICATIONS 2003

WS-10: SURFACE SCIENCE
TOPIC: BIOSURFACES

Ávila, Spain. June 30-July 2, 2003

Aim

One of the most dynamic areas for nano- and surface science and technology is the interface between synthetic materials and living matter. Major application areas are medical implants and devices, biosensors, bioarrays for high throughput screening (HTS) and clinical diagnostics, and various other diagnostic and therapeutic methods involving interfacial phenomena, e.g. NMR, lasers, magnetic nanoparticles etc. Further examples are scaffolds for cell cultures and tissue engineering, and (potentially for the future) bioelectronic devices. Biomimetic approaches in materials science is yet another vivid and rapidly increasing area of research. Scientific issues concern the structure, properties, energetic, and kinetic processes of biological entities of varying complexity at surfaces and interfaces. Examples are water and small biomolecules (amino acids, nucleic acids), peptides, proteins, DNA, self assembled monolayers and supported biomembranes, macromolecular assemblies and cells and tissue. An important component of this area is development or adoption of new analytical and preparative techniques. Examples of the latter are the whole range of nano- and microfabrication techniques, formation of controlled 2D overlayers of biomolecules and micropatterning of such layers, 3D chemical and physical microarchitectures for cell and tissue guidance, and microfluidic patterns. Analytical techniques include the scanning probe microscopies (STM,AFM,SNOM,..) optical (SFG,SHG, FTIR, ellipsometry, SPR;..) and other (piezoelectric, magnetic, calorimetric,...) techniques for bio-interfacial studies, including enhanced sensitivities realizing or approaching single molecule detection. There is also a rapidly increasing need of theory and simulations of biointerfacial properties and processes.

This conference covers a majority of these topics with leading international researchers as invited speakers. It also provides a forum to discuss trends and developments in this challenging and exciting area.